卒業生の方へ_RSSニュースリスト(英) https://www.doshisha.ac.jp/en/news/rss/alumni_newslist.rss 卒業生の方へ_RSSニュースリスト(英) en Copyright(C) Doshisha University All Rights Reserved. Thu, 22 Feb 2024 09:41:14 +0900 http://blogs.law.harvard.edu/tech/rss [Research News] Chemical Synthesis Using Titanium Dioxide: An Eco-Friendly and Innovative Approach
HitomiFig_outline.png Chemical Synthesis Transformed by Solar Light: An Eco-Friendly and Innovative Approach with Titanium Dioxide
A team of researchers now present an eco-friendly and innovative approach for the blue light-promoted synthesis of heterocyclic thiochromenopyrroledione derivatives catalyzed by titanium dioxide.

Hitomi Yutaka, a Professor, and Pijush Kanti Roy, a Ph.D. candidate, both from the Department of Applied Chemistry, Graduate School of Science and Engineering, and their research team propose a new titanium dioxide-catalyzed strategy for synthesizing thiochromenopyrroledione derivatives in blue light.

Thiochromenopyrroledione derivatives, while not yet recognized as a primary structure in pharmaceuticals, contain sulfur, an element frequently found in many drugs, indicating their potential in medicinal applications. Recently, the researchers demonstrated that the blue-light irradiation of 4-substituted thioanisoles and N-substituted maleimides with titanium dioxide as a photocatalyst led to a dual carbon–carbon bond formation reaction. The study presents titanium dioxide as an eco-friendly catalyst for thiochromenopyrroledione derivatives synthesis and advances innovative methods for organic synthesis.


Reference

Kanti Roy P., Okunaka S., Tokudome H., Hitomi Y. Blue Light-Promoted Synthesis of Thiochromenopyrroledione Derivatives via Titanium Dioxide-Catalyzed Dual Carbon–Carbon Bond Formation with Thioanisole and Maleimide Derivatives (2023) Advanced Synthesis and Catalysis
DOI: 10.1002/adsc.202301021

For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Chemical Synthesis Using Titanium Dioxide: An Eco-Friendly and Innovative Approach

Image Credit: Professor Yutaka Hitomi from Doshisha University
License type: Original content
Usage restrictions: Cannot be used without permission.




Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-EntwCy.html Spotlights Mon, 01 Jan 2024 14:00:00 +0900
Doshisha Business School Acquires International Accreditation from AMBA!
amba_logo

Doshisha Business School Acquires International Accreditation from AMBA!

Doshisha Business School (DBS, Graduate School of Business) has obtained international accreditation for its MBA program from AMBA (The Association of MBAs: United Kingdom) on October 18, 2023. Established in 1967 in the UK, AMBA is one of the three most prestigious international accreditation bodies in the world, alongside AACSB (The Association to Advance Collegiate Schools of Business: United States) and EFMD (The European Foundation for Management Development: Belgium). As of October 2023, only about 2% of business schools worldwide, totaling 305 schools, have obtained international accreditation from AMBA. This achievement by Doshisha Business School marks only the fourth Business School in Japan to achieve AMBA accreditation, also making it the first AMBA accredited Business School in the Kansai region. Doshisha Business School (DBS) has formally established its world-class educational quality and research activities through the accreditation evaluation process by such a respected international third party. This international accreditation certifies that the education provided by DBS embodies the spirit of conscientious education and leverages the wisdom that blends Kyoto's tradition and innovation, nurturing leaders possessing high levels of integrity who can also contribute to the sustainable development of economies and societies globally. DBS will continue to utilize AMBA's global network to constantly improve the quality of education that is offered and aim to continue to improve the value that it provides to its students and alumni. Through its unique MBA program, offered in both Japanese and English, DBS promises to nurture leaders who will forge a new era and contribute to the creation of a better society.

AMBA Homepage

Doshisha Business School (DBS, Graduate School of Business) Homepage

日本語 HP

English HP


Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-DAMWRq.html Spotlights Wed, 20 Dec 2023 13:04:54 +0900
[Research News] Reclaiming Carbon Fibers from Discarded Composite Materials
Image Proteostasis Carbon-fiber-reinforced plastics (CFRPs) as energy-efficient structural materials.
Thanks to their light weight yet remarkable strength, the use of CFRPs in the automobile, aerospace, and renewable energy industries is soaring. However, this means finding effective ways to recycle the waste generated by CFRPs is essential to ensure sustainability in the long term.

Kiyotaka Obunai, an Associate Professor, and Kazuya Okubo, a Professor, both from the Department of Mechanical and Systems Engineering of the Faculty of Science and Engineering, have investigated how using superheated steam can help preserve the properties of fibers recovered from waste carbon-fiber-reinforced plastic (CFRP) via thermal decomposition.The demand for CFRPs for aerospace, automotive, and renewable energy applications has recently skyrocketed, creating the need for efficient ways to recycle these composites. Their findings could open doors to more sustainable manufacturing processes and a reduced environmental impact in industries reliant on CFRPs, contributing to a greener future.

Reference
Obunai K., Okubo K. Mechanical characteristics of reclaimed carbon fibre under superheated steam atmosphere and its feasibility for remanufacturing CFRP/CFRTP (2024) Composites Part A: Applied Science and Manufacturing, 176, art. no. 107843
DOI: 10.1016/j.compositesa.2023.107843


For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Reclaiming Carbon Fibers from Discarded Composite Materials

This achievement has also been featured in the “EurekAlert!.”
NEWS RELEASE 16-NOV-2023: Reclaiming Carbon Fibers from Discarded Composite Materials


Image Credit: LunchboxLarry at Openverse
License type: CC BY 2.0


Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-VM0Gy2.html Spotlights Thu, 16 Nov 2023 14:00:00 +0900
[Research News] Study Reveals Novel Therapeutic Target to Eliminate Unwanted and Misfolded Proteins
Image Proteostasis Schematic representation of NRF1-triggered activation of aggrephagy mediated by impaired proteasome activity
The ubiquitin‒proteasome system (UPS) and autophagy are protein degradation pathways essential for maintaining protein balance and regulation, or proteostasis (left panel). When proteasome activity decreases because of several reasons including chemical inhibitors and aging, the transcription factor NRF1 gets activated, leading to the upregulation of proteasome gene expression (“the proteasome bounce-back response;” middle panel). Furthermore, complete proteasome dysfunction activates NRF1-mediated aggrephagy, inducing the expression of the aggrephagy-related genes p62 and GABARAPL1 (right). These cellular responses help combat proteasome dysfunction by maintaining proteostasis.

Atsushi Hatanaka, a graduate student, and Akira Kobayashi, a professor, both from the Laboratory for Genetic Code, Graduate School of Life and Medical Sciences, and their research team discovered the hidden mechanism of "aggrephagy," with major implications for degenerative protein diseases.
In cells, the ubiquitin‒proteasome system (UPS) plays a key role in the elimination of unwanted or misfolded proteins. When UPS fails, cells activate a backup process called "aggrephagy" for clearing ubiquitin-tagged proteins. However, the associated mechanism behind this process remains unknown. Recently, Hatanaka, Kobayashi, and their colleagues have demonstrated how another protein called NRF1 facilitates aggrephagy, thereby providing new therapeutic targets for diseases resulting from misfolded proteins.
These findings pave the way toward developing novel therapeutics for degenerative diseases such as Alzheimer's disease, Parkinson's disease, and dementia with Lewy bodies.

Reference
Hatanaka A., Nakada S., Matsumoto G., Satoh K., Aketa I., Watanabe A., Hirakawa T., Tsujita T., Waku T., Kobayashi A. The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis (2023) Scientific Reports, 13 (1), art. no. 14405
DOI: 10.1038/s41598-023-41492-9

For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Study Reveals Novel Therapeutic Target to Eliminate Unwanted and Misfolded Proteins

This achievement has also been featured in the “EurekAlert!.”
NEWS RELEASE 4-OCT-2023 Study Reveals Novel Therapeutic Target to Eliminate Unwanted and Misfolded Proteins

Image Credit: Atsushi Hatanaka, Sota Nakada, Gen Matsumoto, Katsuya Satoh, Iori Aketa, Akira Watanabe, Tomoaki Hirakawa, Tadayuki Tsujita, Tsuyoshi Waku, and Akira Kobayashi
License type: CC BY 4.0




Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-Jer1y7.html Spotlights Thu, 05 Oct 2023 10:34:06 +0900
[Research News] Unveiling the Science of Ultrasound-Driven Microbubble Desorption
TOC Molecular desorption from a microbubble under ultrasound irradiation.
The amount of molecular desorption can be estimated quantitatively by the proposed method.

A research team headed by Professor Daisuke Koyama and graduate student Ms. Reina Kobayashi, from the Faculty of Science and Engineering, reported, “novel measurement technique can help develop targeted therapeutic strategies that use microbubbles and ultrasound to deliver drugs to specific locations.”
Vascular drug therapies often lead to undesirable side effects on healthy tissues. Addressing this issue requires targeted drug delivery systems. They have recently developed an innovative approach for measuring the amount of molecules desorbed from the surface of individual microbubbles when irradiated with ultrasound. Using this technique, they analyzed the desorption process in detail, revealing insights that could enable the design of next-generation drug delivery systems based on drug-loaded microbubbles and ultrasound.

Reference
I Kobayashi R., Narita J., Nakaoka N., Krafft M.P., Koyama D. Quantitative estimation of phospholipid molecules desorbed from a microbubble surface under ultrasound irradiation (2023) Scientific Reports, 13 (1), art. no. 13693.
DOI: 10.1038/s41598-023-40823-0

For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Unveiling the Science of Ultrasound-Driven Microbubble Desorption

This achievement has also been featured in the “EurekAlert!.”
NEWS RELEASE 21-SEP-2023 Unveiling the Science of Ultrasound-Driven Microbubble Desorption


Image Credit:Daisuke Koyama and Reina Kobayashi
License type: Original content




Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-shhp5F.html Spotlights Thu, 21 Sep 2023 13:30:00 +0900
[Research News] Culture-friendly Therapies for Treating Anxiety and Depression in Japanese Youth
How is cognitive-behavioral therapy applied to young people in Japan?
An example of a comic strip used in culturally adapted cognitive-behavioral therapy for Japanese youth.

Shin-ichi Ishikawa, professor at the Faculty of Psychology, and his colleagues summarize how cognitive-behavioral therapies have been successfully adapted and implemented for youth in Japan.
Although cognitive-behavioral therapies (CBT) have grown in popularity globally, they face barriers to implementation outside Western countries. In a new article, Ishikawa and his colleagues discuss that CBT is being successfully used to treat anxiety disorder and depression among the country’s youth. They also identified the most successful CBT programs and specific strategies for implementing CBT programs in non-Western cultures to improve the quality of life of youth suffering from mental illnesses.

Reference
Ishikawa, Si., Kishida, K., Takahashi, T. et al. Cultural Adaptation and Implementation of Cognitive-Behavioral Psychosocial Interventions for Anxiety and Depression in Japanese Youth. Clin Child Fam Psychol Rev 26, 727–750 (2023).
https://doi.org/10.1007/s10567-023-00446-3

For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Culture-friendly Therapies for Treating Anxiety and Depression in Japanese Youth

This achievement has also been featured in the “EurekAlert!.”
NEWS RELEASE 7-SEP-2023 Culture-friendly Therapies for Treating Anxiety and Depression in Japanese Youth

Image Credit:Shin-ichi Ishikawa and Yoko Kamio
Image Source Link to be added in the Image Credit Section of EA form: http://mentalhealthprogram.jp/
License type: Original content




Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-RguwAb.html Spotlights Fri, 08 Sep 2023 13:26:15 +0900
[Research News] Father-child bonding and its impact on pediatric developmental outcomes
Figure_Kato et al Paternal childcare and its positive impacts on the child’s socio-physical development
Adjusted risk ratios with 95% confidence intervals for the associations of paternal involvement in childcare.

Dr. Tsuguhiko Kato, Researcher, and Dr. Shoji Itakura, Fellow Professor and Director at the Center for Baby Science at Doshisha University, and their colleagues showed the importance of paternal involvement in infant care and its key developmental impacts among Japanese children.
The extent of paternal involvement in childcare has been historically restricted in Japan because of the ingrained gender-based division of labor. However, recent trends show a paradigm shift in paternal parenting attitudes across Japan. A recent study examines paternal care among 6-month-old Japanese infants and its impact on various developmental outcomes at the age of 3 years. The study also assessed the impact of reduction of maternal parenting stress on childcare outcomes.

Reference
Kato T., Fujii M., Kanatani K., Niwa F., Hirabayashi K., Nakayama T., Itakura S., et al. (2023) Paternal involvement in infant care and developmental milestone outcomes at age 3 years: the Japan Environment and Children’s Study (JECS). Pediatr Res.
https://doi.org/10.1038/s41390-023-02723-x


For more details, please see the website of Organization for Research Initiatives and Development, Doshisha University.
Research News: Father-child bonding and its impact on pediatric developmental outcomes

This achievement has also been featured in the “EurekAlert!.”
NEWS RELEASE 24-AUG-2023 Father-child bonding and its impact on pediatric developmental outcomes 


Image Credit: Tsuguhiko Kato from Doshisha University
Image Source Link to be added in the Image Credit Section of EA form: n/a
License type: Original content




Contact

ここにお問い合わせ先名称を入力してください

TEL:XXXX-YY-ZZZZ
FAX:XXXX-YY-ZZZZ
E-mail:xxxxxxxxx@yyy.zzzzz.ac.jp


]]>
https://www.doshisha.ac.jp/en/news/detail/001-DK0noP.html Spotlights Mon, 28 Aug 2023 15:41:44 +0900