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[Research News] Listening in on Neuron Conversations: Novel Fluorescent cAMP Indicator Facilitates Neuronal Live-Cell Imaging

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Updated Jul. 20, 2022
Naoto Saitoh, Associate Professor at the Faculty of Biomedical Sciences, and his colleagues have succeeded in developing a novel fluorescent indicator of cyclic adenosine monophosphate (cAMP) called gCarvi. This can lead to determining cAMP dynamics underlying several neuronal functions.

Reference:
Seiko Kawata, Yuki Mukai, Yumi Nishimura, and Naoto Saitoh, “Green fluorescent cAMP indicator of high speed and specificity suitable for neuronal live-cell imaging”, Proceedings of the National Academy of Sciences (PNAS), 119 (28) e2122618119, July 12, 2022. https://doi.org/10.1073/pnas.2122618119

For more details, please see the link below.
Research News: Listening in on Neuron Conversations: Novel Fluorescent cAMP Indicator Facilitates Neuronal Live-Cell Imaging (Website of Doshisha University Organization for Research Initiatives and Development)


This achievement has also been featured in the “EurekAlert!”.
Listening in on neuron conversations: Novel fluorescent cAMP indicator facilitates neuronal live-cell imaging (EurekAlert!)
Cross-regulation between cAMP/Ca2+ is a fundamental phenomenon in neurons

Cross-regulation between cAMP/Ca2+ is a fundamental phenomenon in neurons
Credit: Naoto Saitoh from Doshisha University
Usage restrictions: Cannot be reused without permission

Naoto Saitoh, Associate Professor at the Faculty of Biomedical Sciences, and his colleagues have succeeded in developing a novel fluorescent indicator of cyclic adenosine monophosphate (cAMP) called gCarvi. This can lead to determining cAMP dynamics underlying several neuronal functions.

Reference:
Seiko Kawata, Yuki Mukai, Yumi Nishimura, and Naoto Saitoh, “Green fluorescent cAMP indicator of high speed and specificity suitable for neuronal live-cell imaging”, Proceedings of the National Academy of Sciences (PNAS), 119 (28) e2122618119, July 12, 2022. https://doi.org/10.1073/pnas.2122618119

For more details, please see the link below.
Research News: Listening in on Neuron Conversations: Novel Fluorescent cAMP Indicator Facilitates Neuronal Live-Cell Imaging (Website of Doshisha University Organization for Research Initiatives and Development)


This achievement has also been featured in the “EurekAlert!”.
Listening in on neuron conversations: Novel fluorescent cAMP indicator facilitates neuronal live-cell imaging (EurekAlert!)
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